13^th World Conference on Human Genomics and Genomic Medicine August 10-11, 2020 Dubai, UAE

Over the past decade there are many advances in genomic technologies,enabling biologists to explore the genetics for research opportunities. One of the most exciting development in fields has been in genome sequencing  assembly, where researchers can now produce assemblies of genomes for the species they select.

A genetic disorder is a condition caused by a deviation in the DNAsequence away from the regular sequence, in whole or in part. Genetic abnormalities may be initiated due to mutation in one gene or in more than one gene or due to environmental factors or due to chromosomal damages.

Human Genome Project originally aimed at mapping nucleotides found in a human haploid reference genome. Each individual's genome is unique; gene mapping the human genome requires sequencing andthen linking them together to produce a full sequence for each chromosome. The human genome is therefore a mosaicwhich is not represented by one person. 

Pharmacogenomics is the study of genome's function in responding to drugs.It is mixture of the genomics and pharmacology. Pharmacogenomics analyzes  how an individual's genetic makeup influences his / her response to drugs. It deals with the effect of genetic variation acquired and inherited ondrug reaction in patients by attributing gene expression or single-nucleotide polymorphisms with pharmacokinetics (drug intake, delivery, metabolism, and elimination) and pharmacodynamic. For certain cases the term pharmacogenomics is used interchangeably with pharmacogenetics.

Oncogenomics is a subfield of the genomics that characterizes the cancer related genes.  Cancer is a genetic disease induced by accumulation of DNA mutations and epigenetic modifications that contribute to unrestrained cell proliferation and development of neoplasms. The aim of oncogenomics is to discover new genes for oncogenes or tumor suppressors that can provide new insights into cancer identification, predict outcomes of clinical cancer and new targets for cancer treatment.The success of targeted cancer therapies like Gleevec, Herceptin, and Avastin  has increased hopes that oncogenomics will elucidate new targets for cancer care.

Gene expression is one of the key molecular mechanisms that control the differentiation, growth and functioning  of  cells and tissues. Gene expression of the brain varies over the various phases of life. Earlydevelopment sees the most  important levels of expression, with the rate of gene expression being the highest during fetal development. This is because of the fast growth of neurons in the embryo.

Differences in the sequence and structure of genomes from members ofa microbial community represent the mutation, recombination, and selection composite effects. With the growing availability of genome sequences, these effects have been better characterized and exploited in order to understand the nature and evolution of microbes and viruses and their often intimate relationships with humans.

Bioinformatics is sharing the origins of computational genomics with others. Computational genomics  analyzes vast databases of biological data, such as genetic sequences, populations of cells or to discover new biologies.

Nutrigenomics studies the genome effect of nutrients, and the response to diet from human genetic makeup.Active dietary molecules and human genetics are two major factors that control the development of chronic diseases like cancer, cardiovascular disorders, diabetics, hypertension and obesity. Adequate nutrient intake protects us from  developing chronic diseases. The nutrients should be kept in the optimal balance between the total oxidation status and the genome's total antioxidant response to maintain a degree of equilibrium between these two variables

Molecular genetics is a genetic subfield that uses genetic screens to determine genetic structure and/or function within an organism's genome using an investigative approach. The research area focuses on the integration of numerous biology subfields like cell biology, molecular biology,biochemistry, and biotechnology. Genomic Medicine   and Healthcare course was planned for healthcare professionals including medical physicians, general practitioners, allied health professionals, nurses, genetic counselors and others with equivalent undergraduate degrees or comparable professional qualifications and background experience.

Biomarkers are the observable predictor showing the particular person's existence, or quantity or extent of the disorder. Existing genomics and biotechnology applications provide assurance of biomarker production to guess the livelihood of disease in an individual ,enable initial disease identification and improve diagnostic classification for better individualized improvement.

Public health practice aims to recognize the causes of the disease,anticipate and avoid it where possible, and or else detect it early and efficiently treat it so as to mitigate morbidity, disability and death. The making of effective epidemiological methods is to look at disease over the past years and its contribution  to the risk factors and providing basic strategies for disease prevention and health promotion