Human Genomics and Genomic Medicine

Genes and Immunology

Genes play a fundamental role in immunology, influencing various aspects of the immune system's function, including its development, regulation, and response to pathogens. The genetic basis of immunology is essential for elucidating the mechanisms underlying immune responses, identifying therapeutic targets for immune-related disorders, and developing personalized approaches to immunotherapy and vaccination. Advances in genomic technologies, such as high-throughput sequencing and genome editing, continue to deepen our understanding of the complex interplay between genes and the immune system.

Genes intersect with immunology includes:

• Genetic basis of immune system development
• Immune receptor genes
• Major histocompatibility complex genes
• Cytokine genes
• Genetic susceptibility to diseases
• Pharmacogenomics of immunomodulatory drugs